Science

The Science of SSRIs

July 1, 2019

We have all heard of SSRIs whether it’s in a good way or a bad one. But what are they? And how do they work? I wanted to dive into this because I myself take an SSRI. It took me a while to commit to trying medication for my anxiety and OCD but now that I have, it’s completely life changing. I should also mention, I’ve worked with my general doctor and therapist on determining the best route for me. It’s important to go through a licensed professional if you think taking medication would work for you.

SSRI stands for selective serotonin reuptake inhibitors. They are commonly prescribed as an antidepressant to overcome depression with few side effects. SSRIs can also be used to treat anxiety as well.

This type of medicine works by increasing the level of serotonin in our brains. Serotonin is a neurotransmitter (chemical messenger) that translates a signal across all brain cells. SSRIs block the reuptake/reabsorption of serotonin allowing for more of the neurotransmitter to be available. This blocking process only works with serotonin and none of the other neurotransmitters.

There are six FDA approved medications that are prescribed to treat depression and anxiety; citalopram, escitalopram, fluoxetine, paroxetine, sertraline, and vilazodone. Each has a brand and generic, both of which contain the same amount of active ingredient (medicine).

For the most part, the side effects for SSRIs are varied and may only occur with some people. Drowsiness, nausea, dry mouth, insomnia, diarrhea, nervousness, sexual issues, headache and blurred vision are the most common side effects. I experienced drowsiness the first few weeks but that went away and I now don’t have any side effects.

It’s important to pay attention to how you feel when taking a medication. If you have certain side effects you may need to try a different type until you find the one that works for you. Always consult your doctor.

I’m very grateful for my therapist and general practitioner who support this decision. It has given me freedom mentally that I have never had. I’m just appreciative of the science and how it’s affected me.  

SSRIs may not be for everyone but for right now they’re working for me.

Xox, Z

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